Sudden drastic changes in the norms of day to day living can trigger an Existential crisis. If it happens as part of a transition from youth to adult, it may be an Identity crisis. If it happens at in the 30’s to 40’s, it might be called a Midlife crisis.
If you’ve started to define your life by your job, or your home, your kids, or your marriage, and suddenly those things go away – then you may have to re-review who you are as a person. You could sing about it.
Of course, you could just go work on the Meaning of Life while you’re going down that hole.